Summary: Listeria monocytogenes is an intracellular bacterium responsible for a disease characterized by distinct clinical features, such as septicemia, brain infection, abortion, and perinatal infection. These clinical features are attributed to its incredible capacity to cross distinct barriers in susceptible hosts. Intracellular infection is a consequence of the bacterium’s capacity to enter a wide variety of mammalian cells, to not only survive however also replicate therein, and to its faculty to spread from one cell to the following, thereby escaping the humoral immune response. Here, we review both the well‐established and the newly learned strategies used by this bacterium …
During the first century, the Roman physician Cornelius Celsus defined four cardinal signs of inflammation: redness, swelling, heat, and pain. These signs and symptoms occur during infection by invasive pathogens or as a consequence of trauma. Today, we know the molecular basis of these physiological responses as mediated by cytokines and other factors produced by cells of the innate immune system. Cytokines are both necessary and sufficient to cause pathophysiological alterations manifested as the four cardinal signs. Importantly, this knowledge has enabled the development of highly selective therapeutical agents that target individual cytokines to prevent or reverse inflammation. For example,... …
Summary: Intracellular pathogens contribute to a significant proportion of infectious disease morbidity and mortality worldwide. Increasing evidence points to a major role for host genetics in explaining inter‐individual variation in susceptibility to infectious diseases. A number of monogenic disorders predisposing to infectious disease have been reported, including susceptibility to intracellular pathogens in association with mutations in genes of the interleukin‐12/interleukin‐23/interferon‐γ axis. Common genetic variants have also been demonstrated to regulate susceptibility to intracellular infection, for example the CCR5Δ32 polymorphism that modulates human immunodeficiency virus‐1 (HIV‐1) disease progression. Genome‐wide association study approaches are being incr... More information: Click here...…
Question by Lovely Latina: I have a sore throat could it be allergies or a bacterial infection?
I suffer from allergies the heat has been on a lot. When I breathe I can feel the air in my throat making it dry. When I drink more water it makes my throat feel better. My nose is a bit runny not much. I also had oral sex with a guy a week ago so I'm concerned that I could have a bacterial infection. Is there any way to know if my soreness is caused by allergies or infection…
Defining the genital immune correlates of protection against HIV acquisition: co-infections and other potential confounders
The sexual transmission of HIV is very inefficient, presumably since mucosal immune defences prevent infection after most exposures. Since numerous genital immune factors have antiviral effects in vitro, their elucidation might greatly inform the microbicide and HIV prevention fields, particularly in the context of HIV-exposed however persistently seronegative (ESN) individuals. However, distinct vital confounders must be considered in such research. First, sound epidemiological criteria are needed to define individuals as ESN. Then, since high-risk sexual activity is commonly one of these criteria, its potential impact on genital immunology must be carefully considered, both the administer effects of sex and the …
There are many yeast infection house remedies available on the internet, which claim to cure you in no age. There is a remedy so effective, that it can cure your infection in hours! More information: Check this...
Question by Circe: Is this allergies or an infection from contacts?
Today I noticed I had a lot of green crust in the corners of my eyes. My allergies were especially bad, but I also just got contacts a month ago, so I am not sure what the cause actually is.
Answer by JacanbaIt also could be your are getting some sort of illness like a sinus infection. Give it a few days to see if it clears up or see if you have other symptoms.
Add your own answer in the comments!…
Question by hardboiled: How can I tell if it's a sinus infection or just allergies?
Its spring in Chicago, but it doesn't seem like flowers are budding, yet I'm sneezing like the big bad wolf! I was wondering if it might be a sinus infection as my nose is clogged and I can hardly breath through it. And how do people tell if it's allergies or a sinus infection?
Answer by HopeWith allergies eyes and nose itch and can water or a stuffy nose.
- Q&A: Is it okay to wear contacts if you have allergies ? 09. Mar, 2011
- Q&A: What is the best over the counter medicine to take for sinus allergies? 26. Jan, 2011
- Can kissing someone for half an hour cure allergies? 30. Mar, 2011
- What should I give to my friend who has a peanut allergy? 17. Mar, 2011
- What is the best laundry detergent for allergy sufferers? 27. Feb, 2011
- Improving paediatric asthma outcomes in primary health care: a randomised controlled trial. 11. Oct, 2011
- Obese Mothers Put Children at Higher Risk of Asthma 11. Oct, 2011
- Home-based educational interventions for children with asthma. 11. Oct, 2011
- Aspirin Desensitization: A "Lifechanger" For Patients With Aspirin And NSAID Allergies; Cardiovascular Disease 11. Oct, 2011
- New Study Aims to Cure Food Allergies 11. Oct, 2011
- formerly_bob: Its possible based on my wife's experience. My wi...
- Sandy K: Drinking after taking any type of medication is a ...
- essentiallysolo: wait six hours after an antihistamine to imbibe al...
- Liam S: Different allergies and asthma quite commonly occu...
- you_me_us16: no,..take it for relief reasons...